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Companies/Spyre Therapeutics, Inc.
Company profile

Spyre Therapeutics, Inc.

NASDAQ: SYRE · Healthcare · Biotechnology
PublicHQ Waltham, MA · MiddlesexCIK 0001636282Reports USD
#1143 of 1,394 Healthcare companies by revenue
EA Score
64C
FH 68DQ 69GM 38SS 66
v0.1 · 65/100 weight · provisional
↑ Altman-Z, balance-sheet leverage · ↓ 3-yr revenue growth, Piotroski F
Methodology →
Revenue TTM
$90.5M
Rev growth YoY (TTM)
needs 8 qtrs
Net income (FY)
-$155.2M
Employees
73
Market cap
$5.2B
OverviewFinancialsSegmentsFilingsESGPeople & Places

Financials — latest annual

SEC EDGAR · USD-normalized
ConceptUSDNativeFY
Revenue$0$02025
Net income-$155.2M-$155.2M2025
Operating income-$209.6M-$209.6M2025
Total assets$777.8M$777.8M2025
Liabilities$62.5M$62.5M2025
Equity$715.2M$715.2M2025

Revenue trend

FY2018 – FY2025 · USD
$3.9M
FY18
$0
FY19
$0
FY20
$18.7M
FY21
$2.3M
FY22
$886.0k
FY23
$0
FY24
$0
FY25

Revenue by segment

Filed disclosures · FY2023
By product
License0%
By geography

Not disclosed.

The read

Spyre Therapeutics, Inc. booked $0 in FY2025 revenue — among the slowest-growing Healthcare companies we track, at a -Infinity% net margin.

Peers · Healthcare
Celcuity Inc.——Caris Life Sciences, Inc.59CTravere Therapeutics, Inc.74BSotera Health Company70B
Neighbors
Middlesex →
GE Vernova Inc.$38.1B63CThermo Fisher Scientific Inc.$44.6B86AAnalog Devices, Inc.$11.0B87AThe TJX Companies, Inc.$60.4B85ABoston Scientific Corporation$20.1B88AAlnylam Pharmaceuticals, Inc.$3.7B79B+
Key facts
CEOCameron Turtle
SectorHealthcare
IndustryBiotechnology
HeadquartersWaltham, MA
ExchangeNASDAQ: SYRE
Employees73
IPO date2016-04-07
Latest filings
8-K2026-06-158-K2026-06-018-K2026-05-298-K2026-05-0510-Q2026-05-058-K2026-04-168-K2026-04-138-K2026-04-13
Financials: SEC EDGAR (XBRL), USD-normalized per IAS 21 · TTM/quarterly + segments: FMP from filed disclosures · Filings: EDGAR submissions. County headcount and EA Score are in progress — see docs/DATA_GAPS.md.
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