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Companies/Spero Therapeutics, Inc.
Company profile

Spero Therapeutics, Inc.

NASDAQ: SPRO · Healthcare · Biotechnology
PublicHQ Cambridge, MA · MiddlesexCIK 0001701108Reports USD
#600 of 1,394 Healthcare companies by revenuetop-decile growth
EA Score
68B
FH 91DQ 52GM 41SS 51
v0.1 · 65/100 weight · provisional
↑ operating margin, net margin · ↓ growth stability, 3-yr revenue growth
Methodology →
Revenue TTM
$54.8M
Rev growth YoY (TTM)
+22.8%
Net income (FY)
$8.6M
Employees
32
Market cap
$127.4M
OverviewFinancialsSegmentsFilingsESGPeople & Places

Financials — latest annual

SEC EDGAR · USD-normalized
ConceptUSDNativeFY
Revenue$12.6M$12.6M2025
Net income$8.6M$8.6M2025
Operating income$6.3M$6.3M2025
Total assets$68.9M$68.9M2025
Liabilities$9.9M$9.9M2025
Equity$59.0M$59.0M2025

Revenue trend

FY2019 – FY2025 · USD
$172.0k
FY19
$4.7M
FY19
$258.0k
FY20
$3.1M
FY21
$48.6M
FY22
$933.0k
FY23
$371.0k
FY24
$12.6M
FY25

Revenue by segment

Filed disclosures · FY2025
By product
Collaboration Revenue Related Party70%
Collaboration Revenue19%
Grant Revenue11%
By geography

Not disclosed.

The read

Spero Therapeutics, Inc. booked $12.6M in FY2025 revenue, growing 3292% year over year — faster than 98% of Healthcare companies we track, at a 68.1% net margin.

Peers · Healthcare
The Joint Corp.75B+Avita Medical Inc.50DMaxCyte, Inc.48DAardvark Therapeutics, Inc. Common Stock40D
Neighbors
Middlesex →
GE Vernova Inc.$38.1B63CThermo Fisher Scientific Inc.$44.6B86AAnalog Devices, Inc.$11.0B87AThe TJX Companies, Inc.$60.4B85ABoston Scientific Corporation$20.1B88AAlnylam Pharmaceuticals, Inc.$3.7B79B+
Key facts
CEOEsther Rajavelu
SectorHealthcare
IndustryBiotechnology
HeadquartersCambridge, MA
ExchangeNASDAQ: SPRO
Employees32
IPO date2017-11-02
Latest filings
8-K2026-06-258-K2026-06-2210-Q2026-05-138-K2026-05-13DEF 14A2026-04-2710-K2026-03-268-K2026-03-268-K2026-01-30
Financials: SEC EDGAR (XBRL), USD-normalized per IAS 21 · TTM/quarterly + segments: FMP from filed disclosures · Filings: EDGAR submissions. County headcount and EA Score are in progress — see docs/DATA_GAPS.md.
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